Oral Manifestations of a Pediatric Patient with Primary Hyperoxaluria Type 1: A Case Report
오승현, 김현태, 신터전, 현홍근, 김영재, 김정욱, 장기택, 송지수,
소속 상세정보
오승현 ( Oh Seung-Hyun ) - Seoul National University School of Dentistry Department of Pediatric Dentistry
김현태 ( Kim Hyun-Tae ) - Seoul National University School of Dentistry Department of Pediatric Dentistry
신터전 ( Shin Teo-Jeon ) - Seoul National University School of Dentistry Department of Pediatric Dentistry
현홍근 ( Hyun Hong-Keun ) - Seoul National University School of Dentistry Department of Pediatric Dentistry
김영재 ( Kim Young-Jae ) - Seoul National University School of Dentistry Department of Pediatric Dentistry
김정욱 ( Kim Jung-Wook ) - Seoul National University School of Dentistry Department of Pediatric Dentistry
장기택 ( Jang Ki-Taeg ) - Seoul National University School of Dentistry Department of Pediatric Dentistry
송지수 ( Song Ji-Soo ) - Seoul National University School of Dentistry Department of Pediatric Dentistry
KMID : 1144020220180010011
Abstract
Primary hyperoxaluria is a rare, genetic metabolic disorder caused by deficiency of alanine-glyoxylate aminotransferase, which results in recurrent kidney stones, parenchymal renal damage, and end-stage renal disease. Patients with primary hyperoxaluria have accumulation of calcium oxalate crystal in most part of the oral cavity, such as bone, periodontal tissues, dentin, cementum, and dental pulp. This report describes a case of 6-year-old boy who was diagnosed with primary hyperoxaluria. For treatment of primary hyperoxaluria, he underwent pre-emptive liver transplant and was on continuous hemodialysis. He has been taking multiple medications, including aspirin. In oral and radiographic examination, generalized root resorption, multiple radiolucent lesions and severe periodontitis were observed. These conditions caused dental pain, worsened tooth mobility, progressive tooth loss and mesial titling of permanent molars. Periodontal treatments including dental scaling were performed under tapered administration of aspirin and prescription of prophylactic antibiotics. Early diagnosis and careful management of the oral conditions would be necessary with the goal of minimizing progression of periodontitis and alveolar bone resorption.
키워드
Primary hyperoxaluria; Oral manifestation; Periodontitis; Root resorption; Tooth loss
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